Created technology for the complete destruction of viruses in donor organs
Today, thousands of people need donor organs, but not all receive them. Perhaps a new virus removal technique will solve this problem, since many of the donated organs do not reach the recipients due to infections that make them unsuitable for transplantation. The technology involves washing their cavities and vessels with a non-toxic liquid preservative and destroying bacteria using two types of light.
The method was coined by Prof. Marcelo Sipel from the University of Toronto. Previously, physicians had already decontaminated organs by replacing blood with a liquid to kill viruses, but this technology was not as effective as we would like. Ultraviolet light was used for blood disinfection – why not combine these technologies together to get the best result?
To translate his ideas into reality, Marcelo Sipel teamed up with Wanderleigh Bagnato of the University of São Paulo, Brazil. They created an apparatus that, as part of a harmless preservative, injects into a liquid infected with viruses that absorbs red light with a wavelength of 660 nanometers. The resulting energy causes damage to the membranes and genetic material even of viruses such as hepatitis C and HIV-1.
In addition to the red light, the device emits and ultraviolet, which affects the constantly circulating inside the body fluid. One liter of solution is very expensive, but it lasts for hundreds of organ flushing.
Laboratory tests have shown that, after a new treatment, the organs unsuitable for transplantation were indeed cleared of dangerous infections. We are talking about ten people who had their lungs decontaminated in a new way – they easily got accustomed, and the recipients did not even have to take antibiotics, while the rest often undergo a three-month course of antiviral drugs.
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